Atorvastatin Lowers C-Reactive Protein and Improves Endothelium-Dependent Vasodilation in Type 2 Diabetes Mellitus
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چکیده
منابع مشابه
Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.
OBJECTIVES We sought to determine whether the antioxidant vitamin C improves endothelium-dependent vasodilation of forearm resistance vessels in patients with insulin-dependent diabetes mellitus. BACKGROUND Endothelium-dependent vasodilation is impaired in patients with diabetes mellitus. Oxidatively mediated degradation of endothelium-derived nitric oxide contributes to abnormal endothelium-...
متن کاملVitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.
Endothelium-dependent vasodilation is impaired in humans with diabetes mellitus. Inactivation of endothelium-derived nitric oxide by oxygen-derived free radicals contributes to abnormal vascular reactivity in experimental models of diabetes. To determine whether this observation is relevant to humans, we tested the hypothesis that the antioxidant, vitamin C, could improve endothelium-dependent ...
متن کاملImpaired endothelium-dependent vasodilation in type 2 diabetes mellitus and the lack of effect of simvastatin.
OBJECTIVE Although type 2 diabetes is recognized as an independent risk factor for cardiovascular disease and cardiovascular disease is associated with endothelial dysfunction, the influence of type 2 diabetes per se on the endothelial function is controversial. HMG-CoA-reductase inhibitors have been shown to have short-term beneficial effects on endothelial dysfunction among patients with dysl...
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Background: Diabetes mellitus, which is associated with elevated blood glucose, lipids and liver enzymes, may results in alterations in the production of inflammatory cytokines, including chitinase-3-like protein 1 (YKL-40) and high-sensitivity C-reactive protein (hs-CRP), which induce and promote complications of diabetes such as atherosclerosis.The aim of this study was to evaluate the serum ...
متن کاملVildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes
OBJECTIVE To investigate whether the dipeptidyl peptidase-4 inhibitor vildagliptin improves endothelium-dependent vasodilatation in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Sixteen subjects with type 2 diabetes (age 59.8 ± 6.8 years, BMI 29.1 ± 4.8 kg/m(2), HbA(1c) 6.97 ± 0.61) on oral blood glucose-lowering treatment were included. Participants received vildagliptin 50 mg b...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2002
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.87.2.8249